Ben Roethlisberger threw for 311 yards and two scores, as the Steelers defeated Denver, 26-21.
Diontae Johnson caught eight passes for 92 yards and a touchdown, while rookie Chase Claypool had three catches for 88 yards, including an 84-yard touchdown.
James Conner ran the ball 16 times for 106 yards.
The Steelers improved to 2-0 and will play host to Houston on Sunday.
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